Get ready to explore bustling squares, ancient buildings and the world's oldest botanical garden on this all-encompassing day tour. In the morning, catch the high-speed train from Venice Santa Lucia train station and reach Padua in just 25 minutes, where you will meet your guide at Piazza Garibaldi. With your guide, discover the treasures of the Padua historic center, starting from Cafè Pedrocchi, a world-famous 18th-century literary cafè. Stroll through the city's lively piazzas, where you will discover a 13th-century university, a Roman cathedral, and an exsquisite astrological clock. Walk through the narrow streets of the Jewish ghetto and learn more about Padua's important role in medieval Jewism, passing by the Prato della Valle, one of the largest squares in Europe. Finally, stop by the Basilica del Santo, which houses the remains of Saint Anthony, patron saint of Padua, where your guide will leave you. Afterward, enjoy some free time to get some lunch before heading to the botanical gardens. Explore the UNESCO World Heritage Site gardens at your own pace before catching the train back to Venice in the evening.